From my point of view, it's ok, if the GIMP ends with an error message explaining something like - No such file. This is actually written in the super long alert window that pops up.
What is not so good are the cases, when GIMP crashes. They might be caused by limited system resources. From the provided error message it looks like insufficient RAM/buffer size.
So my recommendation would be to check the system resources status and use GIMP options as expected.
Best regards
Josef Ridky
Senior Software Engineer
Core Services Team
Red Hat Czech, s.r.o.