The python-qt5 package in RHEL 8 does not ship the webkit package. I'm assuming that this is unlikely to be changed since qt5-qtwebkit isn't in RHEL but is in EPEL.
I think I'm close to producing a python-qt5-epel package here [1] that produces python3-qt5-webkit and would love to hear from people more familiar with the package if this seems like it's reasonable/workable.
I think we're depending on the fact that the RHEL python3-qt5-devel package does ship the WebKit sip files and that these would match up with what this package ships.
It also just seems like webengine isn't in there, or I'm missing what's needed to build it. I also don't need it for my purposes.
[1] - https://copr.fedorainfracloud.org/coprs/orion/python-qt5-epel/
epel-devel@lists.fedoraproject.org