[Bug 447559] New: Review Request: perl-GO-TermFinder - Identify GO nodes that annotate a group of genes with a significant p-value

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Tue May 20 14:49:47 UTC 2008


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https://bugzilla.redhat.com/show_bug.cgi?id=447559

           Summary: Review Request: perl-GO-TermFinder - Identify GO nodes
                    that annotate a group of genes with a significant p-
                    value
           Product: Fedora
           Version: rawhide
          Platform: All
        OS/Version: Linux
            Status: NEW
          Severity: medium
          Priority: medium
         Component: Package Review
        AssignedTo: nobody at fedoraproject.org
        ReportedBy: kanarip at kanarip.com
         QAContact: extras-qa at fedoraproject.org
                CC: fedora-package-review at redhat.com,notting at redhat.com


Spec URL: http://pilot.genomicscenter.nl/genomics/SPECS/perl-GO-TermFinder.spec
SRPM URL: http://pilot.genomicscenter.nl/genomics/el5/SRPMS/perl-GO-TermFinder-0.82-1.el5.src.rpm
Description: This package is intended to provide a method whereby the P-values of a set
of GO annotations can be determined for a set of genes, based on the number
of genes that exist in the particular genome (or in a selected background
distribution from the genome), and their annotation, and the frequency with
which the GO nodes are annotated across the provided set of genes. The
P-value is simply calculated using the hypergeometric distribution as the
probability of x or more out of n genes having a given annotation, given
that G of N have that annotation in the genome in general. We chose the
hypergeometric distribution (sampling without replacement) since it is more
accurate, though slower to calculate, than the binomial distribution
(sampling with replacement).

Additional Information:

This is my first perl package ;-)

- Targeted for EL-5, F-8, F-9 and rawhide. See also koji scratch builds:

- http://koji.fedoraproject.org/koji/taskinfo?taskID=620022 (dist-f8-updates-candidate)
- http://koji.fedoraproject.org/koji/taskinfo?taskID=620032 (dist-f9-updates-candidate)
- http://koji.fedoraproject.org/koji/taskinfo?taskID=620080 (dist-f10)

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