I've been able to figure out that running clamscan from cron.d works with SELinux but rc.local doesn't and one has to use setenforce. I managed to get enough material together to submit Bug #720223 as that just doesn't seem right.
My system now does update and scan on reboot and then cron jobs to periodically run both if my machine is up for a good while (still sorting out good settings for "when")
I dug into SELinux and decided that it is a bit more than I am prepared to experiment with. I get the general idea behind it, but the policy rules are a bit much for a non-sysAdmin sort (and I don't want to run audit2allow as a "catch-all" when the files that will be barking are going to multiple over time, leading to patches on patches on patches).
I also filed a "sug" that clamscan should have a "test error" flag so one can see what happens when it really finds something. Plus a grumble that I found documentation lacking and almost everything I could get was from the web from prior releases (f11, f8 or f9) and not a maintained site.
I wanted to thank everyone for their help as I did learn alot out of this exercise (and hopefully more if I get an answer on my rc.local bug submission), Paul