Persistent static routes

[InvalidPath]

Im having an issue with setting static routes that are persistent.
FOllowing the Fedora documention for 25:
https://docs.fedoraproject.org/en-US/Fedora/25/html/Networking_Guide/sec-...

After some mixup, I set one static route in NetworkManager for my main
Ethernet interface to find the correct filename (instead of route-eth0, it
created route-USB3_Ethernet which is what I named it in NM)

However after subsequent reboots, 'route' does not reflect the routes in
that file.  And I did try both of the syntaxes below to no avail.

ADDRESS0=10.10.10.0
NETMASK0=255.255.255.0
GATEWAY0=192.168.0.10

10.10.10.0/24 via 192.168.0.10 dev eth0